KMID : 1038820240270010037
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Pediatric Gastroenterology, Hepatology & Nutrition 2024 Volume.27 No. 1 p.37 ~ p.42
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Outcomes of Portosystemic Shunts in Children with and without Liver Transplantation
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Hamza Hassan Khan
Stuart S. Kaufman Nada A. Yazigi Khalid M. Khan
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Abstract
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Purpose: Limited data exist regarding outcome and morbidity associated with portosystemic shunts in the pediatric transplant population. Our study assesses the outcomes of pediatric patients who underwent a portosystemic shunt procedure, both with and without liver transplantation (LT).
Methods: This study retrospectively reviewed the medical records of pediatric patients aged 0?19 years who underwent shunt placement between 2003 and 2017 at a tertiary care center. The analysis included cases of shunt placement with or without LT.
Results: A total of 13 pediatric patients were included in the study with median age of 8.8 years. Among the cases, 11 out of 13 (84.6%) underwent splenorenal shunt, 1 (7.7%) underwent a mesocaval shunt, and another 1 (7.7%) underwent a Modified Rex (mesoportal) shunt. Additionally, 5 out of 13 (38.5%) patients had LT, with 4 out of 5 (80.0%) receiving the transplant before shunt placement, and 1 out of 5 (20.0%) receiving it after shunt placement. Gastrointestinal bleeding resulting from portal hypertension was the indication in all cases. A total of 10 complications were reported in 5 patients; the most common complication was anemia in 3 (23.1%) patients. At the most recent follow-up visit, the shunts were functional without encephalopathy, and no deaths were reported.
Conclusion: Shunt placement plays a crucial role in the management of patients with portal hypertension. Our study demonstrates favorable long-term outcomes in pediatric patients who underwent shunt placement. Long term shunt outcomes were similar and unremarkable in patients with LT and without LT.
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KEYWORD
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Hypertension, portal, Liver transplantation, Thrombosis, Biliary atresia, Portosystemic shunt, surgical
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